Covalent binding ligands that reacts with its target protein to form a covalent complex in which the protein has lost its function. Covalent binding ligands can be reversible or
irreversible, highly depending on structural factors (steric and electronic), stability of the complex and reaction conditions...
Covalent binder Database, to our best knowledge, is the first online database that systematically provides information on covalent binding compound structures, chemotypes, targets,
covalent binding types and modes, and other biological properties, and related targets.
Total molecules:   1627
Total drugs:   240
Electrophilic warhead:   74
Total targets:   555
Nucleophilic residues:   23
Related PDBs:   120
Covalent interaction:   2487
Total Referemces:   706
Benchmark data for covalent docking evaluation (BCDE)